Inactive ingredients in drugs and supplements are harming you

CAUTION: "Inactive" Ingredients in Most Common Drugs and Supplements are harming you!

Inactive ingredients are also known as excipients. These  are added to pills and capsules to pad out the active ingredient that you are paying for.

These are commonly chemicals that enable the production machinery to go faster without stoppages. They also increase the volume of the pill or capsule so you think you are getting a bigger bang for your buck.

Inactive ingredients in these type of products can harm you

Excipients in these type of products can harm you. Check the ingredients list VERY carefully.

More excipients than active ingredient

A recent study[1]  has found that the vast majority of the most common prescription drugs  and supplements contain "inactive" ingredients. These extra ingredients have been shown to cause adverse reactions.

Your doctor prescribe drugs for their "active ingredient". The doctor would have told you about the possible side effects of those active ingredients. The same is also true when you go into the health food store to buy your supplements.

What the doctor doesn't tell you is up to 99% of pills and tablets are actually made of "excipients". These excipients are the "inactive" ingredients. They help the drug's appearance, color, flavor, absorption, shelf-life, and other properties. These "inactive" ingredients are only for the benefit of the manufacturers bottom line and not yours.

Read the labels

You need to know that more than 90% of all oral medications tested had at least one such "inactive" ingredient that can cause allergic or gastrointestinal problems, especially to those with certain sensitivities. 

This includes, but is not limited to, ingredients such as chemical dyes... gluten... peanut oil... and lactose. In fact, most medications contain more than one type of inactive ingredients.

If you do take any prescription or OTC medications, do your best to research what their "inactive" ingredients are. Check their possible effects (not just the possible side effects of the main "active" ingredient, in other words.)

Most "inactive" ingredients are shown in the small print in the ingredients list. Common ones are Magnesium Stearate, Rice Flour, Tapioca Flour, Silicon Dioxide, Titanium Dioxide. There are many more of these excipients (see list here) that the FDA have determined are safe for manufacturers to add to their products to increase their profits.

Here is a range of supplements that do not use excipients or any other additives.

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References

  • 1.  Lokesh B, Stefan S, Sheehan C, William R (2006). "Excipients: Background/Introduction". In Katdare A, Chaubal, Mahesh (eds.). Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery SystemsCRC PressISBN 9781420004137OCLC 476062541.
  • Osterberg RE, See NA.Toxicity of excipients--a Food and Drug Administration perspective.Int J Toxicol. 2003 Sep-Oct;22(5):377-80.PMID: 14555410 DOI: 10.1177/109158180302200507

    Steinberg M, Silverstein I.The use of unallowed excipients.Int J Toxicol. 2003 Sep-Oct;22(5):373-5.PMID: 14555409 DOI: 10.1177/109158180302200506

    Parhiz H, Khoshnejad M, Myerson JW, Hood E, Patel PN, Brenner JS, Muzykantov VR. Unintended effects of drug carriers: Big issues of small particles. Adv Drug Deliv Rev. 2018 May;130:90-112. doi: 10.1016/j.addr.2018.06.023. Epub 2018 Jul 3. PMID: 30149885 PMCID: PMC6588191 DOI: 10.1016/j.addr.2018.06.023

    Abrantes CG, Duarte D, Reis CP. An Overview of Pharmaceutical Excipients: Safe or Not Safe? J Pharm Sci. 2016 Jul;105(7):2019-26. doi: 10.1016/j.xphs.2016.03.019. Epub 2016 Jun 1. PMID: 27262205 DOI: 10.1016/j.xphs.2016.03.019

    Pifferi G, Restani P. The safety of pharmaceutical excipients. Farmaco. 2003 Aug;58(8):541-50. PMID: 12875883 DOI: 10.1016/S0014-827X(03)00079-X

    Yuan CJ, Marikawa Y. Developmental toxicity assessment of common excipients using a stem cell-based in vitro morphogenesis model. Food Chem Toxicol. 2017 Nov;109(Pt 1):376-385. doi: 10.1016/j.fct.2017.09.023. Epub 2017 Sep 18. PMID: 28927898 PMCID: PMC5656506 DOI: 10.1016/j.fct.2017.09.023

    Pérez-Ibarbia L, Majdanski T, Schubert S, Windhab N, Schubert US. Safety and regulatory review of dyes commonly used as excipients in pharmaceutical and nutraceutical applications. Eur J Pharm Sci. 2016 Oct 10;93:264-73. doi: 10.1016/j.ejps.2016.08.026. Epub 2016 Aug 12. PMID: 27531552 DOI: 10.1016/j.ejps.2016.08.026

    Chen ML. Lipid excipients and delivery systems for pharmaceutical development: a regulatory perspective. Adv Drug Deliv Rev. 2008 Mar 17;60(6):768-77. Epub 2007 Nov 12. PMID: 18077051 DOI: 10.1016/j.addr.2007.09.010

    Pouton CW, Porter CJ. Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies. Adv Drug Deliv Rev. 2008 Mar 17;60(6):625-37. Epub 2007 Nov 4. PMID: 18068260 DOI: 10.1016/j.addr.2007.10.010

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